What are the symptoms of glycogen storage disease in cats?
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Asked By: Molly Chew
Date created: Tue, Oct 18, 2022 8:38 AM
Date updated: Sun, May 12, 2024 17:48 PM
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Best answer to the question «What are the symptoms of glycogen storage disease in cats?»
In cats, type IV glycogen storage disease is apparent in Norwegian Forest cats, and often results in death before birth. If your cat survives this condition, symptoms can include fever, muscle tremors, and weakness.
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How do you diagnose type 4 glycogen storage disease in cats?Type IV, the type found in cats, results from a deficiency of the glycogen branching enzyme. Diagnosis. Diagnostic procedures will vary depending on the symptoms and suspected type of glycogen storage disease at hand. A tissue enzyme analysis and determination of glycogen levels can serve as a definitive diagnosis.
What is glycogen storage disease in cats?
Glycogenosis in Cats. Glycogen storage disease, also known as glycogenosis, is a rare inherited disorder with various types, all characterized by deficient or defective activity of the enzymes responsible for metabolizing glycogen in the body. This leads to an abnormal accumulation of glycogen, the main carbohydrate storage material in...
What is glycogen storage disease type IV?
Glycogen Storage Disease Type IV is caused by a branching enzyme deficiency that causes an inability to metabolize glucose properly, resulting in an accumulation of an abnormal form of glycogen in the muscles and liver.
What causes glycogen storage disease type IV in Norwegian Forest cats?
A glycogen storage disease type IV resulting from deficiency of glycogen branching enzyme occurs as an autosomal recessive trait in Norwegian Forest cats. Although glycogen storage occurs in multiple organ systems in the cat, it is dysfunction of skeletal muscle, cardiac muscle, and nervous tissue that characterizes the feline disorder.
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What is glycogen storage disease type IV (GSD IV)?
The fourth classification pertains only to cats and so is commonly referred to as Glycogen Storage Disease Type IV, or GSD IV, but can also be known as glycogenosis. Glycogen molecules normally act as carbohydrate storage and convert to glucose whenever the body is in need of energy.
What is glycogen storage disease?
Glycogen storage disease is a rare, inherited metabolic disease that can affect both people and animals. In people and most animals, the condition falls into one of three types depending on the type of enzyme deficiency.
What are the different types of glycogen storage disease in cats?
In people and most animals, the condition falls into one of three types depending on the type of enzyme deficiency. The fourth classification pertains only to cats and so is commonly referred to as Glycogen Storage Disease Type IV, or GSD IV, but can also be known as glycogenosis.
What kind of disease is glycogenosis in cats?
Glycogenosis in Cats. Glycogen storage disease, also known as glycogenosis, is a rare inherited disorder with various types, all characterized by deficient or defective activity of the enzymes responsible for metabolizing glycogen in the body.
What to do if your cat has glycogen storage disease?
Treatment of Glycogen Storage Disease in Cats. If your cat is determined to have GSD IV, the main condition to be treated is hypoglycemia, which is a deficiency of glucose in the blood (low blood sugar). Close monitoring and a change to a high carbohydrate diet will be the first to be addressed.
What happens if a cat has glycogen storage type 4?
Although glycogen storage occurs in multiple organ systems in the cat, it is dysfunction of skeletal muscle, cardiac muscle, and nervous tissue that characterizes the feline disorder. In contrast, glycogen storage type IV of humans typically results in early-onset and progressive hepatic cirrhosis and liver failure.
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What is type IV glycogen storage disease in cats?
The Type IV classification found in cats is seen in the Norwegian Forest breed. Signs may manifest at five to seven months of age, or in some cases, the disease may manifest in the womb, resulting in a still birth. In cats, type IV glycogen storage disease is apparent in Norwegian Forest cats, and often results in death before birth.
What is glycogen accumulation?
This leads to an abnormal accumulation of glycogen, the main carbohydrate storage material in the body which aids short term energy storage in cells by converting to glucose as the body needs it for metabolic requirements.
What kind of disease does a Norwegian Forest cat have?
In cats, type IV glycogen storage disease is apparent in Norwegian Forest cats, and often results in death before birth. If your cat survives this condition, symptoms can include fever, muscle tremors, and weakness. The various forms of glycogenoses all result from some sort of deficiency in glucose-metabolizing enzymes in the body.
Do Norwegian Forest cats have health problems?
Norwegian forest cats are generally very healthy, but there are a few conditions that this breed seems prone to: Glycogen Storage Disease IV: This is a heritable condition that is often fatal. Hip Dysplasia: While more common in dogs, this large cat may also be at risk for this disease.
Why do cats with gum disease refuse to eat?
By the time they start showing symptoms, such as refusing food, the gum disease can be well advanced. In addition to the high plant content in commercial cat food is the very poor quality animal protein – rejects from the more lucrative human market, where storage and hygiene are not considered important.. Yet cats need high quality animal protein.
What causes glycogen deficiency in Norwegian Forest cats?
The one cause of GSD IV was originally due to inbreeding. This led the genetic line of Norwegian Forest cats (and eventually select other, closely related cats who bred with Norwegian Forest cats) to have a deficiency of a glycogen branching enzyme that aids in glycogen metabolism.
What happens when glycogen accumulates in the body?
Accumulation of glycogen in the tissues can result in the enlargement and dysfunction of various organs, including the liver, heart, and kidneys. The Type IV classification found in cats is seen in the Norwegian Forest breed.
Do all cats with heartworm disease show symptoms?
Not all cats with heartworm disease show symptoms. Some cats are able to spontaneously rid themselves of heartworms without having any symptoms. However, some infected cats die suddenly from heartworm disease without ever showing signs of being sick. Cats with heartworm disease may have very nonspecific symptoms that mimic many other cat diseases.
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